Hydroxychloroquine Formulation Patent

Chloroquine phosphate usp is an antimalarial and. Other uses include treatment of rheumatoid arthritis lupus and porphyria cutanea tarda.

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It is used to prevent and provide short term treatment of malaria and long term treatment of other diseases such as rheumatoid arthritis lupus and porphyria cutanea tarda.

Hydroxychloroquine formulation patent. Hydroxychloroquine plaquenil and its sister drug chloroquine are under investigation for treatment of the covid 19 coronavirus disease. Plaquenil hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate equivalent to 155 mg administration. Concordia approved prior to jan 1 1982 strengths.

Dibasic calcium phosphate usp hypromellose usp magnesium stearate nf polyethylene glycol 400 nf polysorbate 80 nf corn starch titanium dioxide usp. Assignment of assignors interest see document for. Plaquenil is a brand name of hydroxychloroquine approved by the fda in the following formulations.

Hydroxychloroquine therapy has not been associated with liver function abnormalities and is an extremely rare cause of clinically apparent acute liver injury. Deepa es origiin ip solutions llp hydroxychloroquine also termed as hydroxychloroquine sulfate is a white crystalline powder that is freely soluble in water and is an antimaterial drug. It is taken by mouth.

It is freely soluble in water practically insoluble in alcohol in chloroform and in ether. It is also being studied as a treatment for coronavirus disease 2019 covid 19. Has a generic version of plaquenil been approved.

Hydroxychloroquine sulfate is the generic ingredient in two branded drugs marketed by alkaloida zrt amneal pharms co hikma pharms invatech ipca labs ltd laurus labs ltd lupin ltd mylan sandoz teva pharms twi pharms watson labs zydus pharms usa inc and concordia and is included in fourteen ndas. Google patents the invention relates to new preparation of hydroxychloroquine sulfate and particularly provides a hydroxychloroquine sulfate capsule and a hydroxychloroquine sulfate dispersible. It is a white crystalline powder odorless has a bitter taste and is discolored slowly on exposure to light.

Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. Korean doctors used these anti malaria drugs to treat covid 19 with some success according to a paper filed with elsevier in march 2020 but effectiveness is unprovenhydroxychloroquine is classified as an anti malarial drug. Plaquenil hydroxychloroquine sulfate tabletoral manufacturer.

Hydroxychloroquine hcq sold under the brand name plaquenil among others is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Chloroquine phosphate usp is a 4 aminoquinoline compound for oral administration. 1994 05 24 publication of us5314894a publication critical patentus5314894aen 1996 11 25 assigned to sanofi sa.

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