Other uses include treatment of rheumatoid arthritis lupus and porphyria cutanea tarda. Hydroxychloroquine sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties hydroxychloroquine sulfate acts against erythrocytic malarial parasites plasmodium vivax ovale and malariae by concentrating in food vacuoles.
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Hydroxychloroquine hcq sold under the brand name plaquenil among others is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine.
Hydroxychloroquine structure and chemical name. Hydroxychloroquine s c18h26cln3o cid 178396 structure chemical names physical and chemical properties classification patents literature biological. Hydroxychloroquine is whats known as an analog of chloroquine meaning the two have similar structures but different chemical and biological properties. Hydroxychloroquine is a 4 aminoquinoline with immunosuppressive antiautophagy and antimalarial activities.
Hydroxychloroquine is a drug that was used originally to treat malaria especially in patients who could not tolerate the similar compound chloroquine. The approved drug is a racemic mixture and we show the chemical structure without stereochemistry to represent the mixture. Although the precise mechanism of action is unknown hydroxychloroquine may suppress immune function by interfering with the processing and presentation of antigens and the production of cytokines.
Atc anatomical therapeutic chemical classification p01ba02. It is taken by mouth. More recently it has been used as a component of antiwrinkle skin.
It is also being studied as a treatment for coronavirus disease 2019 covid 19. Cas registry number chemical abstracts service 0000118 42 3. Hydroxychloroquine sulphate 200mg tablets leaflet scheme.
2010 is the root structure of the energy tranfer coenzymes atp and adp. Disease modifying antirheumatic drug dmard. Hydroxychloroquine is a 4 aminoquinoline and used primarily as an antimalarial drug.
It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. The former is considered the less toxic.
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